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Anti-ASB17含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族17抗体
点击次数：177发布时间：2012/12/26 3:54:47
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-9135R
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详细内容
货号：BY-9135R
英文名称：Anti-ASB17
中文名称：含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族17抗体
其他名称：Ankyrin repeat ａnd SOCS box containing 17;Ankyrin repeat ａnd SOCS box protein 17;ASB-17;ASB17;ASB17_HUMAN.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 34kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cow, dog
产品介绍：Members of the suppressor of cytokine signaling （SOCS） family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins ａnd their binding partners with the Elongin B ａnd C complex. Several other families of proteins also contain SOCS boxes, but differ from the SOCS proteins in the type of domain they contain upstream of the SOCS box. The largest family of SOCS box-containing proteins is the ankyrin repeat ａnd SOCS box-containing （ASB） protein family. Members of the ASB family include ASB-1 through ASB-18 ａnd are involved in a variety of biological processes. ASB-17 is a 295 amino acid member of this family. ASB-17 contains one ankyrin repeat ａnd one SOCS box domain. ASB-17 is thought to be a substrate-recognition subunit of a SCF-like ECS （Elongin-Cullin-SOCS-box protein） E3 ubiquitin protein ligase complex. This complex mediates the ubiquitination of target proteins ａnd their subsequent proteasomal degradation.
