产品展示
Anti-ASB12含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族12抗体
点击次数：189发布时间：2012/12/26 3:55:12
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-9129R
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货号：BY-9129R
英文名称：Anti-ASB12
中文名称：含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族12抗体
其他名称：ankyrin repeat ａnd SOCS box-containing 12;ankyrin repeat ａnd SOCS box-containing protein 12;ankyrin repeat domain-containing SOCS box protein Asb-12;ASB12;FLJ39577.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 34kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cow
产品介绍：Members of the suppressor of cytokine signaling （SOCS） family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins ａnd their binding partners with the Elongin B/C complex. Several other families of proteins also contain SOCS boxes, but differ from the SOCS proteins in the type of domain they contain upstream of the SOCS box. The largest family of SOCS box-containing proteins is the ankyrin repeat ａnd SOCS box-containing （ASB） protein family. ASB-12 （ankyrin repeat ａnd SOCS box-containing 12） is ag 309 amino acid member of the ASB family that contains one SOCS box domain ａnd five ANK repeats. ASB-12 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination ａnd subsequent proteasomal degradation of target proteins.
