产品展示
Anti-AFP(A4)甲胎蛋白单克隆抗体(检测)
点击次数：181发布时间：2012/12/26 4:20:37
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BYm-1622M
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详细内容
货号：BYm-1622M
英文名称：Anti-AFP（A4）
中文名称：甲胎蛋白单克隆抗体（检测）
其他名称：Alpha Fetoprotein; AFP; alpha 1 fetoprotein; alpha fetoglobulin; alpha Fetoprotein; Alpha fetoprotein precursor; FETA; HPAFP.
抗体来源：Mouse
克隆类型：monoclonal克隆号A4
蛋白分子量：predicted molecular weight: 6.4-7.0kDa
纯化方法：affinity purified by Protein A
交叉反应：hu
产品介绍：Alpha 1 Fetoprotein is a major plasma protein produced by the yolk sac ａnd the liver during fetal life. Alpha fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, ａnd the alpha fetoprotein ａnd albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha fetoprotein is found in monomeric as well as dimeric ａnd trimeric forms, ａnd binds copper, nickel, fatty acids ａnd bilirubin. The level of alpha fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida ａnd anencephaly. Expression has been documented in human adrenal, liver, ovary, testis, ａnd pancreas. ESTs have been isolated from normal human brain, liver/spleen, embryo ａnd uterus tissue libraries.Subunit : Dimeric ａnd trimeric forms have been found in addition to the monomeric form.Subcellular Location : Secreted.Tissue Specificity : Plasma. Synthesized by the fetal liver ａnd yolk sac.Similarity : Belongs to the ALB/AFP/VDB family. Contains 3 albumin domains.AFP是由胚胎卵黄囊细胞，胚胎肝细胞和胎儿肠道细胞合成的一种糖蛋白。主要用于原发性或转移性肝细胞癌、肝样胃癌和性腺或性腺外某些生殖细胞肿瘤（如内胚窦瘤）的诊断和鉴别诊断。 AFP敏感度较低，特异性强，大约60%左右的肝细胞肝癌阳性，在低分化肿瘤中常呈阳性表达。该抗体与bsm-1621M（包被）（Anti-Alpha Fetoprotein）配对使用；主要用于ELISA试剂盒，胶体金试剂条制备生产都很好。大量订购可来电商议。
