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Anti-ASBT/SLC10A2顶膜钠依赖性胆盐转运体蛋白抗体
点击次数:400发布时间:2012/12/26 4:25:41
更新日期:2024/9/5 14:43:27
所 在 地:其它
产品型号:BY-4189R
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货号:BY-4189R
英文名称:Anti-ASBT/SLC10A2
中文名称:顶膜钠依赖性胆盐转运体蛋白抗体
其他名称:Apical sodium dependent bile acid transporter; Apical sodium- dependent bile acid transporter; ASBT; IBAT; ileal apical sodium-dependent bile acid transporter; Ileal sodium dependent bile acid transporter; Ileal sodium-dependent bile acid transporter; Ileal sodium/bile acid cotransporter; ISBT; Na+ bile acid cotransporter; Na+ dependent ileal bile acid transporter; NTCP2; Sodium/taurocholate cotransporting polypeptide, ileal; solute carrier family 10 (sodium/bile acid cotransporter family); Solute carrier family 10 member 2.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 38kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, hrs, dog
产品介绍:SLC10A2 plays a critical role in reabsorption of bile acids from the the small intestine lumen. Passive flow of sodium ions down their concentration gradient is coupled to bile acid movement, resulting in an increase in the concentration of bile acids in the interior of the cell. This action conserves the body's pool of re-circulating bile acid. SLC10A2 also plays a key role in cholesterol metabolism as cholesterol is the precursor molecule in bile acid synthesis mediated by CYP7A and FXR.