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Anti-APBB2/FE65L1铁蛋白Fe65样蛋白1抗体
点击次数：249发布时间：2012/12/26 4:30:27
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-11627R
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货号：BY-11627R
英文名称：Anti-APBB2/FE65L1
中文名称：铁蛋白Fe65样蛋白1抗体
其他名称：Amyloid beta （A4） precursor protein-binding, family B, member 2 （Fe65 like）;Amyloid beta A4 precursor protein binding family B member 2;Amyloid beta A4 precursor protein-binding family B member 2;APBB 2;APBB2;APBB2_HUMAN;Fe65 like 1;Fe65 like;Fe65 like protein;FE65L 1;FE65L;FE65L1;Protein Fe65-like 1;Rirl 1;Rirl1;TR2 L;TR2L;Zfra;Zinc finger like protein.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 83kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：Fe65L is a 758 amino acid protein that contains one WW domain ａnd two PID domains. Binding to the intracellular domain of the ∫-Amyloid precursor protein, Fe65L is thought to modulate the internalization and, therefore, the accessibility ａnd function of ∫-Amyloid. Via its ability to control the intracellular accumulation of ∫-Amyloid, Fe65L is thought to play a role in the pathogenesis of Alzheimer＇s disease. Multiple isoforms of Fe65L exist due to alternative splicing events. The gene encoding Fe65L maps to human chromosome 4, which encodes nearly 6% of the human genome ａnd has the largest gene deserts （regions of the genome with no protein encoding genes） of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington＇s disease, Ellis-van Creveld syndrome, methylmalonic acidemia ａnd polycystic kidney disease.Function : May modulate the internalization of beta-amyloid precursor protein.Similarity : Contains 2 PID domains.Contains 1 WW domain.
