本公司经销ACBD/Diazepam Binding Inhibitor，乙酰辅酶A结合蛋白抗体，克隆类型为polyclonal，宿主来源是Rabbit，ACBD/Diazepam Binding Inhibitor乙酰辅酶A结合蛋白抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-11658R
英文名称：Anti-ACBD/Diazepam Binding Inhibitor
中文名称：乙酰辅酶A结合蛋白抗体
其他名称：ACBD 1;ACBD1;ACBP;ACBP_HUMAN;Acyl CoA binding domain containing 1;Acyl CoA binding protein;Acyl Coenzyme A binding domain containing 1;acyl coenzyme A binding protein;Acyl-CoA-binding protein;acyl-Coenzyme A binding domain containing 1;CCK RP;CCKRP;Cholecystokinin releasing peptide trypsin sensitive;DBI;Diazepam-binding inhibitor;endozepine;EP;GABA receptor modulator acyl Coenzyme A binding protein;GABA receptor modulator.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 10kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：Long chain acyl-CoA esters （LCAs） act as both substrates ａnd intermediates in metabolism, ａnd as regulators of various intracellular functions. Acyl-CoA binding protein （ACBP） specifically binds to LCA with high affinity ａnd regulates its availability. ACBP is structurally ａnd functionally conserved among a diverse group of organisms, including human, rat, frog, insect, plant ａnd yeast. DBI, the gene encoding human ACBP, which maps to chromosome 2, is highly expressed in liver, soleus muscle ａnd heart. The ACBP protein is also abundant in cells with a high level of lipogenesis ａnd de novo fatty acid synthesis. Expression of ACBP is significantly induced during adipocyte differentiation. In addition to acyl-CoA binding ａnd transport, ACBP is also implicated in g-aminobutyric acid type A receptor binding, steroidogenesis ａnd peptide hormone release.Function : Binds medium- ａnd long-chain acyl-CoA esters with very high affinity ａnd may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine （BZD） recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.Tissue Specificity : Isoform 1 is ubiquitous, with a moderate expression level. Isoform 2 is ubiquitous with high level in liver ａnd adipose tissue. Isoform 3 is ubiquitous with strong expression in adipose tissue ａnd heart.Similarity : Belongs to the ACBP family.Contains 1 ACB （acyl-CoA-binding） domain.