产品展示
Anti-APR3/C2orf28凋亡相关蛋白3抗体
点击次数：213发布时间：2012/12/26 4:42:18
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-9806R
优质供应
详细内容
货号：BY-9806R
英文名称：Anti-APR3/C2orf28
中文名称：凋亡相关蛋白3抗体
其他名称：Apoptosis related protein 3;Apoptosis related protein APR 3;APR 3;APR3;Chromosome 2 open reading frame 28;HSPC013;p18;PRO240.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 18kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：APR3, also known as C2orf28 or p18, is a 229 amino acid single-pass membrane protein that contains one EGF-like domain ａnd exists as two alternatively spliced isoforms. Expressed at a low level in hematopoietic cell lines, APR3 is thought to be involved in apoptosis ａnd may also play a role in hematopoietic development ａnd differentiation. The gene encoding APR3 maps to human chromosome 2, which houses over 1,400 genes ａnd comprises nearly 8% of the human genome. Harlequin icthyosis, a rare ａnd morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 ａnd ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstr鰉 syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.Subcellular Location : Cell membrane; Single pass membrane protein.
