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Anti-ATG4A自噬相关蛋白4A抗体
点击次数：189发布时间：2012/12/26 4:43:08
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-3873R
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详细内容
货号：BY-3873R
英文名称：Anti-ATG4A
中文名称：自噬相关蛋白4A抗体
其他名称：ATG4A is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form （form II）. Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine （PE）-conjugated form, ａnd has the capacity for the binding to autophagosomes.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 45kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cow, Rb
产品介绍：ATG4A is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form （form II）. Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine （PE）-conjugated form, ａnd has the capacity for the binding to autophagosomes.Function : Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form （form II）. Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine （PE）-conjugated form, ａnd has the capacity for the binding to autophagosomes. Preferred substrate is GABARAPL2 followed by MAP1LC3A ａnd GABARAP.Subcellular Location : Cytoplasm （Probable）.Tissue Specificity : Widely expressed, at a low level, ａnd the highest expression is observed in skeletal muscle ａnd brain. Also detected in fetal liver.Similarity : Belongs to the peptidase C54 family.
