产品展示
Anti-A Raf/ARAFA-Raf抗体
点击次数:279发布时间:2012/12/26 4:52:39
更新日期:2024/9/5 14:43:27
所 在 地:其它
产品型号:BY-2251R
优质供应
详细内容
货号:BY-2251R
英文名称:Anti-A Raf/ARAF
中文名称:A-Raf抗体
其他名称:A raf 1; A-Raf; Raf1; A Raf proto oncogene serine/threonine protein kinase; ARAF 1; ARAF; ARaf proto oncogene serine/threonine protein kinase; ARAF1; Oncogene Araf1; Oncogene PKS2; PKS 2; PKS; PKS2; Proto oncogene Pks; RAFA 1; RAFA1; Ras binding protein DA Raf; v raf murine sarcoma 3611 viral oncogene homolog; v raf murine sarcoma 3611 viral oncogene homolog 1; v raf oncogene homolog 1 (murine sarcoma 3611 virus).
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 68kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, rat, mo
产品介绍:The RAF family of signaling proteins has three isoforms: A RAF, RAF 1 and B RAF. These proteins are instrumental in forwarding the stimulus generated by mitogens from monomeric G proteins to the MAP kinase pathway. RAF 1 is known to be downstream of Ras and binds to it by an N terminal noncatalytic domain. This domain is conserved in A RAF and B RAF. 14-3-3 is also known to be an activator of RAFs. Activated RAF directly phosphorylates and activates MEK. A RAF is expressed at a very high concentration in urogenital and kidney tissues.