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Anti-Phospho-A Raf(Ser299)磷酸化A-Raf抗体
点击次数：398发布时间：2012/12/26 4:53:09
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-3371R
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货号：BY-3371R
英文名称：Anti-Phospho-A Raf（Ser299）
中文名称：磷酸化A-Raf抗体
其他名称：A raf 1; A Raf proto oncogene serine/threonine protein kinase; ARAF 1; ARAF; ARaf proto oncogene serine/threonine protein kinase; ARAF1; Oncogene Araf1; Oncogene PKS2; PKS 2; PKS; PKS2; Proto oncogene Pks; RAFA 1; RAFA1; Ras binding protein DA Raf; v raf murine sarcoma 3611 viral oncogene homolog; v raf murine sarcoma 3611 viral oncogene homolog 1; v raf oncogene homolog 1 （murine sarcoma 3611 virus）.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 67kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, dog, cow, shp, pig, hrs, Rb
产品介绍：The RAF family of signaling proteins has three isoforms: A RAF, RAF 1 ａnd B RAF. These proteins are instrumental in forwarding the stimulus generated by mitogens from monomeric G proteins to the MAP kinase pathway. RAF 1 is known to be downstream of Ras ａnd binds to it by an N terminal noncatalytic domain. This domain is conserved in A RAF ａnd B RAF. 14-3-3 is also known to be an activator of RAFs. Activated RAF directly phosphorylates ａnd activates MEK. A RAF is expressed at a very high concentration in urogenital ａnd kidney tissues.Function : Involved in the transduction of mitogenic signals from the cell membrane to the nucleus.Subunit : Interacts with TH1L/NELFD.Tissue Specificity : Predominantly in urogenital tissues.Similarity : Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.Contains 1 phorbol-ester/DAG-type zinc finger. Contains 1 protein kinase domain. Contains 1 RBD （Ras-binding） domain.
