本公司经销Ankyrin G，锚定蛋白G抗体，克隆类型为polyclonal，宿主来源是Rabbit，Ankyrin G锚定蛋白G抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-2415R
英文名称：Anti-Ankyrin G
中文名称：锚定蛋白G抗体
其他名称：ANK-3;ANK3;ANK3_HUMAN;ankyrin 3 （G）;Ankyrin 3, node of Ranvier （ankyrin G）;Ankyrin 3, node of Ranvier;Ankyrin G119;Ankyrin-3;Ankyrin-G;brain specific ankyrin G;CHANK3.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 481/220kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, pig, cow, dog, hrs, Rb
产品介绍：human: Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton ａnd play key roles in activities such as cell motility, activation, proliferation, contact, ａnd the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; ａnd a carboxy-terminal regulatory domain which is the least conserved ａnd subject to variation. Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 ａnd 2, ａnd was originally found at the axonal initial segment ａnd nodes of Ranvier of neurons in the central ａnd peripheral nervous systems. Alternatively spliced variants may be expressed in other tissues. Although multiple transcript variants encoding several different isoforms have been found for this gene, the full-length nature of only two have been characterized. [provided by RefSeq] mouse: This gene encodes a member of the ankyrin protein family. Ankyrins link integral membrane proteins to the spectrin-based Ankyrins link integral membrane proteins to the spectrin-based cytoskeleton. Ankyrin family members share a protein structure which includes three independently folded domains: the N-terminal ankyrin repeat domain, the central spectrin-binding domain, ａnd the C-terminal rod domain. This ankyrin functions as the major ankyrin in the kidney ａnd may play a role in the polarized distribution of many integral membrane proteins to specific subcellular sites. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.Function : Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels ａnd cell adhesion molecules at the nodes of Ranvier ａnd axonal initial segments.Subcellular Location : Cytoplasm > cytoskeleton.Tissue Specificity : Expressed in brain, neurons ａnd other tissues.锚定蛋白G是一个分子量在480KDa大分子细胞内蛋白。锚蛋白（ankyrin）锚蛋白属于联结蛋白家族,广泛存在于各种组织细胞中。锚蛋白连接整合膜蛋白到细胞骨架蛋白网络,在多种细胞功能活动中起关键作用,参与机体生长、发育、细胞内蛋白转运、细胞极性的建立和维持、细胞黏附、信号传导以及mRNA转录等。