本公司经销Actin α/alpha-SMA，肌动蛋白α（α-SMA）抗体，克隆类型为polyclonal，宿主来源是Rabbit，Actin α/alpha-SMA肌动蛋白α（α-SMA）抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-0189R
英文名称：Anti-Actin α/alpha-SMA
中文名称：肌动蛋白α（α-SMA）抗体
其他名称：alpha smooth muscle Actin; Actin alpha; ASMA; α Actin; A-SMA; α SMA; α-SMA; ASM-A; alpha-SMA; alpha SMA; AAT6; ACTA2; Actin alpha 2 smooth muscle aorta; Actin aortic smooth muscle; ACTSA; ACTVS; Alpha 2 actin; Alpha cardiac actin; Alpha-actin 2; Cell growth inhibiting gene 46 protein; Growth inhibiting gene 46;ACTA_HUMAN;Actin alpha 2 smooth muscle aorta;Actin aortic smooth muscle;Actin, aortic smooth muscle;Alpha 2 actin;Alpha actin 2;Alpha cardiac actin;Alpha-actin 2;Alpha-actin-2;Cell growth inhibiting gene 46 protein;Cell growth-inhibiting gene 46 protein;Growth inhibiting gene 46;MYMY5.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 42kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cat, chk, cow, dog, Fsh, Gpig, Hm, Mmot, Op, pig, Rb, shp
产品介绍：Actin alpha 2, the human aortic smooth muscle actin gene, is one of six different actin isoforms which have been identified.Actins are highly conserved proteins that are involved in cell motility, structure ａnd integrity. Alpha actins are a major constituent of the contractile apparatus.Subcellular Location : PolyclonalTissue Specificity : Detected in serum ａnd cerebrospinal fluid （at protein level）. Highly expressed in choroid plexus epithelial cells. Detected in retina pigment epithelium ａnd liver.结构蛋白（Structural Proteins）Actin α/α-Actin 是一种具有收缩能力的微丝蛋白，a-SMA广泛分布于几乎所有的肌型细胞中。Actin-α蛋白主要用于检测骨骼肌、平滑肌、血管平滑肌、心肌和肌原性肿瘤 包括：平滑肌瘤、平滑肌肉瘤、横纹肌肉瘤以及肌上细胞和肌上皮瘤。Actin（肌动蛋白）是在所有真核细胞中都表达的高度保守的蛋白质。它们沿微管组成了细胞骨架的主要成分。肌动蛋白至少表达为6种异构形式。它在心脏、骨骼横纹肌组织和某些平滑肌组织中表达，调节其收缩功能。有报导说肌动蛋白在乳房瘤中是高度磷酸化的。肌动蛋白的功能失调也会导致某种类型的心脏病。平滑肌α肌动蛋白使人更感兴趣，因为编码它的基因是相对局限于在血管平滑肌细胞中表达的少数几个基因。肌动蛋白是标记平滑肌和肌上皮细胞肿瘤的有效工具。产品图片Protein: line1, rat brain lysates, 30ug; line2, rat kidney lysates, 30ug; Primary: Anti-alpha-SMA （bs-0189R） at 1:300; Secondary: HRP conjugated Goat-Anti-Rabbit IgG（bse-0295G） at 1: 3000; ECL excitated the fluorescence; Predicted band size : 42kDObserved band size : 42kD