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Anti-Aryl Hydrocarbon Receptor/AHR芳香烃受体抗体
点击次数:238发布时间:2012/12/26 5:02:03
更新日期:2024/9/5 14:43:27
所 在 地:其它
产品型号:BY-1416R
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货号:BY-1416R
英文名称:Anti-Aryl Hydrocarbon Receptor/AHR
中文名称:芳香烃受体抗体
其他名称:Ah receptor; AHR; Aromatic hydrocarbon receptor; Aryl hydrocarbon receptor; Aryl hydrocarbon receptor precursor; BHLHE76; Class E basic helix loop helix protein 76; HGNC:348.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 93kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, rat, mo
产品介绍:This gene encodes a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Its ligands included a variety of aromatic hydrocarbons.转录调节因子(Transcriptin Regulators)芳香烃受体(AHR)是一种配体激活转录因子,可介导多环芳烃类化合物的毒性(包括致癌性)反应,还参与一些重要的生物学过程,如信号转导、细胞分化、细胞凋亡等。人体的肺、肝、肾、胎盘、腭扁桃体、B淋巴细胞等各种组织和细胞中都存在AHR。AHR对生长发育和生理功能等具有调控作用,在一些癌症(乳腺癌和卵巢癌等)发生发展中起促进作用。