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Anti-phospho-ANTXR1(Tyr382)磷酸化肿瘤血管内皮标志物8抗体
点击次数：158发布时间：2012/12/26 5:10:29
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-5210R
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详细内容
货号：BY-5210R
英文名称：Anti-phospho-ANTXR1（Tyr382）
中文名称：磷酸化肿瘤血管内皮标志物8抗体
其他名称：Anthrax toxin receptor 1; Anthrax toxin receptor 1 precursor; ANTXR 1; ANTXR1; ATR; TEM-8; TEM 8; Tumor Endothelial Marker 8; Tumor endothelial marker 8 precursor.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 45kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, rat, mo
产品介绍：TEM8 is a type I transmembrane protein ａnd is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has also been shown to be a docking protein or receptor for Bacillus anthracistoxin, the causative agent of the disease, anthrax. The binding of the protective antigen （PA） component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor（EF） ａnd lethal factor （LF） disrupt normal cellular processes. Three alternatively spliced variants have been described.肿瘤血管内皮标志物8是I型跨膜蛋白，是一种肿瘤特异性血管内皮标记蛋白。
