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Anti-ABCG8三磷酸腺苷结合转运蛋白G超家族成员8抗体
点击次数：227发布时间：2012/12/26 5:16:50
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-5014R
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详细内容
货号：BY-5014R
英文名称：Anti-ABCG8
中文名称：三磷酸腺苷结合转运蛋白G超家族成员8抗体
其他名称：ATP binding cassette sub family G （WHITE） member 8 （sterolin 2）; ATP binding cassette sub family G member 8; MGC142217; Sterolin 2; STSL.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 76kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, pig, cow, hrs, dog, Rb
产品介绍：The protein encoded by this gene is a member of the superfamily of ATP-binding cassette （ABC） transporters. ABC proteins transport various molecules across extra- ａnd intra-cellular membranes. ABC genes are divided into seven distinct subfamilies （ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White）. This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol ａnd sterols into bile, ａnd to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, ａnd gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation ａnd atherosclerosis, ａnd have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008].
