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Anti-ANGEL1ANGEL1蛋白抗体
点击次数：232发布时间：2012/12/26 5:26:55
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-9741R
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详细内容
货号：BY-9741R
英文名称：Anti-ANGEL1
中文名称：ANGEL1蛋白抗体
其他名称：ANGE1_HUMAN;ANGEL1;KIAA0759;mKIAA0759;Protein angel homolog 1;angel homolog 1;RGD1306238.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 75kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：ANGEL1 , also known as KIAA0759, is a 670 amino acid protein belonging to the CKR-4 protein family. ANGEL1 is encoded by a gene located on human chromosome 14, which contains about 700 genes ａnd 106 million base pairs, making up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 （PSEN1） gene, which is one of three key genes associated with the development of Alzheimer＇s disease. The SERPINA1 gene is located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications ａnd liver dysfunction. Notably, the immunoglobulin heavy chain locus on chromosome 14 ａnd its fusion via translocation with the chromosome 19 encoded protein BCL3 may be related to B-cell malignancies.
