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Anti-ANGEL2ANGEL2蛋白抗体
点击次数:290发布时间:2012/12/26 5:27:19
更新日期:2024/9/5 14:43:27
所 在 地:其它
产品型号:BY-9742R
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详细内容
货号:BY-9742R
英文名称:Anti-ANGEL2
中文名称:ANGEL2蛋白抗体
其他名称:ANGE2_HUMAN;Angel homolog 2;angel2;Protein angel homolog 2.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 62kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat
产品介绍:ANGEL2 is a 544 amino acid protein that belongs to the CCR4/nocturin family and exists as two alternatively spliced isoforms. The CCR4 family of proteins are 3′–5′-deadenylases that function in the first step of the degradation of poly(A) mRNA. The CCR4 family most likely displays both RNA and ssDNA substrate preferences, thereby implicating a potential role in many regulatory processes. The ANGEL2 gene maps to human chromosome 1 (1q32.3), which is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. Chromosome 1 contains about 3,000 genes, and considering the great number of genes there are also a large number of diseases associated with it. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons disease, Gaucher disease and Usher syndrome are also associated with chromosome 1.