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Anti-ANKLE2ANKLE2蛋白抗体
点击次数：154发布时间：2012/12/26 5:27:43
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-9743R
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货号：BY-9743R
英文名称：Anti-ANKLE2
中文名称：ANKLE2蛋白抗体
其他名称：ANKL2_HUMAN;ANKLE 2;ANKLE2;ankyrin repeat ａnd LEM domain containing 2;Ankyrin repeat ａnd LEM domain-containing protein 2;LEM domain containing 7;LEMD 7;LEMD7.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 104kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias ａnd hereditary spherocytosis. ANKLE2 （ankyrin repeat ａnd LEM domain containing 2）, also known as LEMD7, is a 938 amino acid single-pass membrane protein containing an ANK repeat ａnd a LEM domain. Exsiting as two isoforms produced by alternative splicing events, the gene encoding ANKLE2 maps to human chromosome 12, which encodes over 1,100 genes ａnd comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases ａnd afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome ａnd trisomy 12p, which causes facial developmental defects ａnd seizure disorders.Subcellular Location : Membrane.
