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Anti-ARHGAP24Rho GTP酶激活蛋白24抗体
点击次数:220发布时间:2012/12/26 5:28:35
更新日期:2024/9/5 14:43:27
所 在 地:其它
产品型号:BY-5785R
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货号:BY-5785R
英文名称:Anti-ARHGAP24
中文名称:Rho GTP酶激活蛋白24抗体
其他名称:ARHGAP24; Filamin A associated RhoGAP; FILGAP; p73; p73RhoGAP; RAC1 and CDC4 specific GTPase activating protein of 72kDa; RCGAP72; Rho GTPase activating protein 24; Rho type GTPase activating protein 24; Rho GTPase-activating protein 24; RhoGAP of 73 kDa; Sarcoma antigen NY SAR 88.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 84kDa
纯化方法:affinity purified by Protein A
交叉反应:hu
产品介绍:ARHGAP24 is a rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. It acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. It controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. There are five different isoforms.Isoform 1 is widely expressed with a higher level in kidney. Isoform 2 is mainly expressed in endothelial cells and is involved in modulation of angiogenesis.