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货号：BY-5777R
英文名称：Anti-ACTRIC/Activin A Receptor Type IC
中文名称：激活素受体1C抗体
其他名称：Activin A receptor, type IC; Activin receptor like kinase 7; Activin receptor type 1C precursor; Activin receptor type IC; Activin receptor type-1C; Activin receptor-like kinase 7; ACTR IC; ACTR-IC; ACTRIC; ACV1C_HUMAN; Acvr1c; ACVRLK7; ALK 7; ALK-7; ALK7.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 52kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, pig, dog, cow, Rb
产品介绍：Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II ａnd 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate ａnd activate type I receptors which autophosphorylate, then bind ａnd activate SMAD transcriptional regulators, SMAD2 ａnd SMAD3. Receptor for activin AB, activin B ａnd NODAL. Plays a role in cell differentiation, growth arrest ａnd apoptosis.Subunit : Binds the type 2 receptor protein ACVR2A.Subcellular Location : Membrane; Single-pass type I membrane protein.Tissue Specificity : Present in pancreas, heart, colon, small intestine, ovary ａnd the hippocampus, medulla oblongata ａnd putamen of the brain. Isoform 1, isoform 2, isoform 3 ａnd isoform 4 are all expressed in the placenta throughout pregnancy.Similarity : Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.Contains 1 GS domain.Contains 1 protein kinase domain.
