产品展示
Anti-alpha 2 Macroglobulinα2巨球蛋白(α-2M)抗体
点击次数：198发布时间：2012/12/26 5:29:48
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-9505R
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详细内容
货号：BY-9505R
英文名称：Anti-alpha 2 Macroglobulin
中文名称：α2巨球蛋白（α-2M）抗体
其他名称：A2M; A2MG_HUMAN; Alpha 2 M; Alpha 2M; Alpha-2-M; Alpha-2-macroglobulin; C3 ａnd PZP-like alpha-2-macroglobulin domain-containing protein 5; CPAMD5; DKFZp779B086; FWP007; S863 7.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 160kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, hrs, cow, chk, pig, Rb
产品介绍：Is able to inhibit all four classes of proteinases by a unique ＇trapping＇ mechanism. This protein has a peptide stretch, called the ＇bait region＇ which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates （activity against high molecular weight substrates is greatly reduced）. Following cleavage in the bait region a thioester bond is hydrolyzed ａnd mediates the covalent binding of the protein to the proteinase.Subcellular Location : SecretedTissue Specificity : Secreted in plasmaSimilarity : Belongs to the protease inhibitor I39 （alpha-2-macroglobulin） family.
