产品展示
Anti-API5凋亡抑制因子5抗体
点击次数：440发布时间：2012/12/26 5:33:29
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-1252R
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详细内容
货号：BY-1252R
英文名称：Anti-API5
中文名称：凋亡抑制因子5抗体
其他名称：apoptosis inhibitor 5; apoptosis inhibitory protein 5; API5; AAC-11; AAC11; API5L1; AAC 11; Antiapoptosis clone 11 protein; API5 like 1; Cell migration inducing gene 8 protein; Fibroblast growth factor 2 interacting factor 2; FIF; Migration inducing protein MIG8; MIG 8; MIG8; Protein XAGL.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 57kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, rat, mo
产品介绍：Apoptosis inhibitor 5 （API5） is an antiapoptotic factor which may have a role in protein assembly. API5 expression is often upregulated in tumor cells, particularly in metastatic cells. It is a critical determinant of E2F1-induced apoptosis, acting downstream of E2F to suppress E2F-dependent apoptosis without generally blocking E2F-dependent transcription. Alternate Names: AAC 11; AAC11; Antiapoptosis clone 11 protein; API 5; API5; API5 like 1; API5L1; Cell migration inducing gene 8 protein; Fibroblast growth factor 2 interacting factor 2; FIF; MIG 8; MIG8; Migration inducing protein MIG8; Protein XAGL.Subunit : Monomer. Interacts with FGF2 ａnd ACIN1.Subcellular Location : Nucleus. Cytoplasm. Note=Mainly nuclear. Can also be cytoplasmic. Isoform 3: Cytoplasm.Tissue Specificity : Expressed in all tissues tested, including heart, brain, placenta, lung, liver, skeletal muscle, kidney ａnd pancreas. Highest levels in heart, pancreas ａnd placenta. Highly expressed in several cancers. Preferentially expressed in squamous cell carcinoma versus adenocarcinoma in non-small cell lung cancer.Similarity : Belongs to the API5 family.IAP-5是细胞凋亡的一种抑制因子、参与细胞凋亡调控，可以用于各种恶性肿瘤的细胞凋亡的研究.
