产品展示
Anti-ASMTLASMTL蛋白抗体
点击次数：218发布时间：2012/12/26 5:38:26
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-9112R
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详细内容
货号：BY-9112R
英文名称：Anti-ASMTL
中文名称：ASMTL蛋白抗体
其他名称：Acetylserotonin N methyltransferase like;Acetylserotonin O methyltransferase like;ASMTLX;ASMTLY;ASTML;N acetylserotonin O methyltransferase like protein.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 69kDa
纯化方法：affinity purified by Protein A
交叉反应：hu
产品介绍：Serotonin, a monoamine neurotransmitter associated with neuronal modulation of emotions, is synthesized by serotonergic neurons of the central nervous system through metabolism of the essential amino acid L-tryptophan. In the pineal gland, serotonin can be transformed into the circadian regulatory hormone melatonin by ASMT （acetylserotonin O-methyltransferase） which catalyzes the final reaction in the synthesis pathway. ASMTL （N-acetylserotonin O-methyltransferase-like protein） is a 621 amino acid protein with a putative catalytic S-adenosyl-L-methionine domain that shares high genetic homology to ASMT. The ASMTL protein is encoded by a gene from the PAR1 region of the X ａnd Y chromosomes, which is considered to be a fusion product of two evolutionarily disparate genes. ASMTL, with potential cytoplasmic localization, is abundant in pancreas, placenta, fibroblast, thymus, prostate, testis, ovary ａnd colon. Low expression levels are found in spleen, small intestine ａnd leukocytes.Subcellular Location : Cytoplasmic
