产品展示
Anti-ANKRD6/Diversin锚蛋白重复域6抗体
点击次数：281发布时间：2012/12/26 5:49:03
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-8728R
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详细内容
货号：BY-8728R
英文名称：Anti-ANKRD6/Diversin
中文名称：锚蛋白重复域6抗体
其他名称：ANKRD 6;ankyrin repeat domain 6.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 85kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cow
产品介绍：Diversin, also known as ANKRD6 （ankyrin repeat domain 6）, is a 727 amino acid protein that contains eight ankyrin repeats ａnd belongs to the ankyrin repeat domain protein family. Members of the ankyrin repeat domain family facilitate protein-protein interactions ａnd function as adaptors of signaling pathways. Expressed in a developmentally-regulated manner ａnd at highest levels in the brain, Diversin is believed to play a role in brain development. Via its ankyrin repeats, Diversin can directly interact with Dvl （dishevelled）, an interaction that is essential for the activation of noncanonical Wnt signaling. In addition, Diversin contains a C-terminal domain that binds Axin/Conductin ａnd a casein kinase-binding domain in its central region that specifically binds casein kinase Ié. Through the action of these additional domains, Diversin may also facilitate canonical Wnt signaling. Due to alternative splicing events, three Diversin isoforms exist.
