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Anti-Bdkrb2/B2R缓激肽B2受体抗体
点击次数:251发布时间:2012/12/26 6:09:25
更新日期:2024/9/5 14:43:27
所 在 地:其它
产品型号:BY-2422R
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货号:BY-2422R
英文名称:Anti-Bdkrb2/B2R
中文名称:缓激肽B2受体抗体
其他名称:B2; B2 bradykinin receptor; B2BKR; B2BRA; B2R; BDKR B2; BDKRB 2; Bdkrb2; BK 2; BK 2 receptor; BK R2; BK2; BK2 receptor; BK2R; BKR 2; BKR2; BR B2; Bradykinin receptor b2; Bradykinin receptor beta 2; BRB 2; BRB2; DKFZp686O088; Kinin B2 Bradykinin receptor beta 2.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 43kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat
产品介绍:Bradykinin increases vascular permeability, dilates blood vessels, contracts non-vascular smooth muscle, and causes pain. This product detects a receptor for bradykinin. The receptor is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. Bradykinin B2 receptor expression has been reported in blood, brain, eye, kidney, liver, lung,prostate, skin, small intestine, synovium, uterus, and vessel. ESTs have been isolated from colon, connective tissue, heart, heart/melanocyte/uterus, kidney, lung, placenta, and thyroid libraries.Function : Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.Subunit : Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.Subcellular Location : Cell membrane; Multi-pass membrane protein.Tissue Specificity : Ubiquitous. Widespread in normal smooth muscle tissue and neurons.Similarity : Belongs to the G-protein coupled receptor 1 family. Bradykinin receptor subfamily. BDKRB2 sub-subfamily.缓激肽B2受体目前主要在糖尿病肾病的发生、发展中起着重要作用。