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Anti-BTG2/TIS21B细胞迁移基因2抗体
点击次数：195发布时间：2012/12/26 6:15:54
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-0031R
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详细内容
货号：BY-0031R
英文名称：Anti-BTG2/TIS21
中文名称：B细胞迁移基因2抗体
其他名称：B-cell translocation gene 2; BTG family, member 2; BTG2; NGF-inducible protein TIS21; NGF-inducible anti-proliferative protein PC3; PC3; TIS21; Agl; An; an-1; Protein BTG2; Pc3.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 17kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, pig, Rb, Gpig
产品介绍：BTG2 is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. BTG2 is involved in the regulation of the G1/S transition of the cell cycle. It modulates transcription regulation mediated by ESR1（referenced from Entrez Gene）. BTG2 expression is induced in vivo during neurogenesis, ａnd the gene is transiently expressed in vitro in rat pheochromocytoma PC12 cells after induction of neuronal differentiation by addition of nerve growth factor （NGF）; suggesting that BTG2 is functionally significant during the neuronal differentiation process （PMID: 12360398）. Function : Involved in cell cycle regulation. Could be involved in the growth arrest ａnd differentiation of the neuronal precursors （By similarity）. Anti-proliferative protein. Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization ａnd neurite outgrowth.Subunit : Interacts with PRKCABP （By similarity）. Binds the CCR4-NOT complex. Interacts with PIN1, inducing mitochondrial depolarization.Similarity : Belongs to the BTG family.产品图片Antigen: bs-0031P, 0.2ug/100ul Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Goat-Anti-Rabbit IgG（bs-0295G-HRP） at 1: 5000; TMB（C-0024） staining; Read the data in MicroplateReader by 450nm.
