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Anti-Bestrophin 3卵黄状黄斑病蛋白3抗体
点击次数：164发布时间：2012/12/26 6:29:02
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-11042R
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详细内容
货号：BY-11042R
英文名称：Anti-Bestrophin 3
中文名称：卵黄状黄斑病蛋白3抗体
其他名称：Vitelliform macular dystrophy 2 like protein 3;BEST 3;BEST3;BEST3_HUMAN;Bestrophin-3;Bestrophin3;Vitelliform macular dystrophy 2 like 3;Vitelliform macular dystrophy 2-like protein 3;VMD2L3.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 51kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, chk, cow, dog, pig
产品介绍：Bestrophin-3 is a 668 amino acid member of the Bestrophin family of proteins. Members of the Bestrophin family are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP （arg-phe-pro） motif ａnd they function as anion channels. Expressed predominantly in skeletal muscle but also found in spinal cord, brain, testis, thymus, retina ａnd bone marrow, Bestrophin-3 forms calcium-sensitive chloride channels. In addition, Bestrophin-3 contains an AI （auto-inhibitory） domain that is capable of regulating the anion channel activity. Due to alternative splicing events, three isoforms exist for Bestrophin-3.Function : Forms calcium-sensitive （By similarity） chloride channels. Permeable to bicarbonate.Subcellular Location : Cell membrane.Tissue Specificity : Present in skeletal muscle ａnd weakly in brain, spinal cord, bone marrow ａnd retina.Similarity : Belongs to the bestrophin family.
