产品展示
Anti-BMPERBMP内皮细胞调节蛋白抗体
点击次数：228发布时间：2012/12/26 6:36:37
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-6910R
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详细内容
货号：BY-6910R
英文名称：Anti-BMPER
中文名称：BMP内皮细胞调节蛋白抗体
其他名称：BMP binding endothelial regulator; BMP binding endothelial regulator precursor protein; Bone morphogenetic protein binding endothelial cell precursor derived regulator; CRIM3; Crossveinless 2; CV 2; CV2; hCV2; Protein crossveinless 2.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 72kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, dog, cow, pig, Rb
产品介绍：This gene encodes a secreted protein that interacts with, ａnd inhibits bone morphogenetic protein （BMP） function. It has been shown to inhibit BMP2- ａnd BMP4-dependent osteoblast differentiation ａnd BMP-dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis. [provided by RefSeq, Dec 2011].BMPER is a BMP-binding protein that is expressed by endothelial cell precursors, has BMP-antagonizing activity, ａnd may play a role in endothelial cell differentiation by modulating local BMP activity. It may also regulate BMP responsiveness in osteoblasts ａnd chondrocytes.Subunit : Interacts with BMP4.Subcellular Location : Secreted.Tissue Specificity : Highly expressed in lung, ａnd brain ａnd also in primary chondrocytes.Similarity : Contains 1 TIL （trypsin inhibitory-like） domain. Contains 5 VWFC domains. Contains 1 VWFD domain.
