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Anti-Phospho-BMX/ETK (Tyr556)磷酸化非受体性蛋白酪氨酸激酶ETK抗体
点击次数:264发布时间:2012/12/26 6:45:50
更新日期:2024/9/5 14:43:27
所 在 地:其它
产品型号:BY-5223R
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货号:BY-5223R
英文名称:Anti-Phospho-BMX/ETK (Tyr556)
中文名称:磷酸化非受体性蛋白酪氨酸激酶ETK抗体
其他名称:BMX; NKT38; NTK 38; Protein tyrosine kinase BMX; PSCTK 2; PSCTK 3; PSCTK2; PSCTK3; Bone marrow tyrosine kinase gene in chromosome X protein; BMX non receptor tyrosine kinase; Cytoplasmic tyrosine protein kinase BMX; Epithelial and endothelial tyrosine kinase.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 74kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, cow, hrs, dog, pig, Rb
产品介绍:Tyrosine kinases are either receptor molecules, which contain transmembrane and extracellular domains, or nonreceptor proteins, which are located intracellularly. BMX[ETK] is a member of Bruton's tyrosine kinase family. It is expressed in haematopoetic, epithelial and endothelial cells and participates in multiple signal transduction pathways.Subunit : Interacts with BCAR1, CAV1, MYD88, PTK2/FAK1, RUFY1, RUFY2, STAT3, TIRAP and TNFRSF1B.Subcellular Location : Cytoplasm.Tissue Specificity : Highly expressed in cells with great migratory potential, including endothelial cells and metastatic carcinoma cell lines.Similarity : Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily. Contains 1 Btk-type zinc finger. Contains 1 PH domain. Contains 1 protein kinase domain. Contains 1 SH2 domain.Etk属非受体性蛋白酪氨酸激酶BTK家族成员,主要表达于上皮和内皮细胞,在调控细胞的增殖及凋亡等信号转导过程中起着重要的作用。Etk与肿瘤发生发展、分化增值密切相关。