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Anti-BACH1/BRIP1乳腺癌易感基因相互作用蛋白1抗体
点击次数：183发布时间：2012/12/26 6:47:13
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-4092R
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货号：BY-4092R
英文名称：Anti-BACH1/BRIP1
中文名称：乳腺癌易感基因相互作用蛋白1抗体
其他名称：BACH 1; BRIP1; BACH-1; BRAC 1 Associated C Terminal Helicase 1; BRCA 1 Interacting Protein 1; BRCA1 binding helicase like protein BACH1; BRCA1 interacting protein C terminal helicase 1; BRIP 1; BRIP-1; FANCJ; ATP dependent RNA helicase BRIP1; Fanconi anemia group J protein; FLJ90232; MGC126521; MGC126523; OF antibody Protein FACJ.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 81kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, Rb, cow, pig, hrs, dog, chk
产品介绍：BACH1 is a member of the DEAH helicase family that interacts with BRCA1, in vivo. BACH1 is a DNA-dependent ATPase ａnd 5＇ to 3＇ DNA helicase required for the maintenance of chromosomal stability. BACH1 acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination, ａnd is involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1. The BACH1/BRCA1 complex formation contributes to a key function of BRCA1. Therefore, it is likely that BACH1 is a target of germline cancer-inducing mutations.Function : Transcriptional regulator that acts as repressor or activator. Binds, in-vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation ａnd repression by MAFK.Subcellular Location : Nucleus.Similarity : Belongs to the bZIP family. CNC subfamily.Contains 1 BTB （POZ） domain. Contains 1 bZIP domain.
