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Anti-BASP1/Nap22脑富含膜附着信号蛋白1抗体
点击次数：303发布时间：2012/12/26 6:54:53
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-8662R
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货号：BY-8662R
英文名称：Anti-BASP1/Nap22
中文名称：脑富含膜附着信号蛋白1抗体
其他名称：BASP 1; BASP-1; BASP1 protein; Brain abundant membrane attached signal protein 1; Brain Abundant Signal Protein Membrane Attached 1; Brain Acid Soluble Protein 1; CAP 23; CAP23; MGC8555; NAP 22; NAP-22; NAP22; Neuronal axonal membrane protein NAP 22; Neuronal tissue enriched acidic protein; 22 kDa neuronal tissue enriched acidic protein.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 25kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, chk, cow, pig, dog, hrs, Rb
产品介绍：Neuronal axonal membrane protein Nap-22, also designated neuronal tissue-enriched acidic protein or brain acid soluble protein （BASP1）, is a Ca2+-dependent calmodulin-binding protein that is important for neuronal sprouting ａnd plasticity. Nap-22 is abundant in brain nerve terminals ａnd is also present in significant amounts in kidney, testis ａnd lymphoid tissue. Nap-22 undergoes N-terminal myristoylation for membrane localization. It has been characterized as a major protein of neuronal rafts, which are known to preferentially bind membranes containing cholesterol. Nap-22 is a crucial protein active in neurite outgrowth ａnd synaptic plasticity.Function : BASP1 is a brain abundant membrane bound protein with several transient phosphorylation sites ａnd PEST motifs. BASP1 binds calmodulin, is phosphorylated by protein kinase C ａnd undergoes N-terminal myristoylation. BASP1 is expressed specifically in nervous tissue. Intercellular signaling ａnd nerve outgrowth are influenced by a number of proteins expressed at nerve endings ａnd synapses of which BASP1 is one. Subcellular Location : Cell membrane; Lipid-anchor. Cell projection, growth cone. Note=Associated with the membranes of growth cones that form the tips of elongating axons.Tissue Specificity : BrainSimilarity : Belongs to the BASP1 family.
