本公司经销BAZ/ACF1，溴区结构域相邻锌指蛋白1A抗体，克隆类型为polyclonal，宿主来源是Rabbit，BAZ/ACF1溴区结构域相邻锌指蛋白1A抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-6476R
英文名称：Anti-BAZ/ACF1
中文名称：溴区结构域相邻锌指蛋白1A抗体
其他名称：BAZ1A; Acf1; ACF1, drosophila, homolog of antibody ATP dependent chromatin remodelling protein; ATP utilizing chromatin assembly ａnd remodeling factor 1; ATP-dependent chromatin-remodeling protein; ATP-utilizing chromatin assembly ａnd remodeling factor 1; Baz1a; BAZ1A_HUMAN; Bromodomain adjacent to zinc finger domain 1A; Bromodomain adjacent to zinc finger domain protein 1A; cbp146; CHRAC subunit ACF1; Gtl5.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 171kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, pig, cow, dog, Rb
产品介绍：Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate evenly spaced nucleosomes along the chromatin. The ATPase activity of the complex is regulated by the length of flanking DNA. Also involved in facilitating the DNA replication process. BAZ1A is the accessory, non-catalytic subunit of the complex which can enhance ａnd direct the process provided by the ATPase subunit, SMARCA5, probably through targeting pericentromeric heterochromatin in late S phase. Moves end-positioned nucleosomes to a predominantly central position. May have a role in nuclear receptor-mediated transcription repression.Component of the histone-fold protein complex CHRAC complex which faciliates nucleosome sliding by the ACF complex ａnd enhances ACF-mediated chromatin assembly. The C-terminal regions of both CHRAC1 ａnd POLE1 are required for these functions.Subunit : Component of the ACF chromatin remodeling complex that includes BAZ1A ａnd SMARCA5. Additional this complex can form, together with CHRAC1 ａnd POLE1, the histone-fold protein complex, CHRAC. Interacts with NCOR1 （via its RD1 domain）; the interaction corepresses a number of NCOR1-regulated genes.Subcellular Location : Nucleus. May target the CHRAC complex to heterochromatin.Tissue Specificity : Highly expressed in testis ａnd at low or undetectable levels in other tissues analyzed.Similarity : Belongs to the WAL family.Contains 1 bromo domain.Contains 1 DDT domain.Contains 1 PHD-type zinc finger.Contains 1 WAC domain.