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Anti-BCAS1/NABC1乳腺癌相关蛋白1抗体
点击次数：226发布时间：2012/12/26 7:01:26
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-11462R
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详细内容
货号：BY-11462R
英文名称：Anti-BCAS1/NABC1
中文名称：乳腺癌相关蛋白1抗体
其他名称：AIBC 1;AIBC1;Amplified ａnd overexpressed in breast cancer;BCAS 1;BCAS1;BCAS1_HUMAN;Breast carcinoma amplified sequence 1;Breast carcinoma-amplified sequence 1;Novel amplified in breast cancer 1.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 62kDa
纯化方法：affinity purified by Protein A
交叉反应：hu
产品介绍：NaBC1 is a protein found amplified in most breast carcinoma forms. It is expressed primarily as a cytoplasmic, detergent-stable homodimer that has a tendency to interact with DYNLL1 （PIN） ａnd DYNLL2. Breast tumor lines that exhibit 20q13.2 gene amplification express much higher levels of the protein as compared to the levels found in other breast cancer lines that do not overexpress the NaBC1 mRNA. However, this upregulation does not affect growth rate or anchoring abilities of a cell, indicating the oncogenic properties of NaBC1 differ from that of other oncogenes.Function : Expressed in brain ａnd prostate, ａnd at lower levels in testis, intestine ａnd colon. Overexpressed in most breast cancer cell lines ａnd down-regulated in some colorectal tumors.Subcellular Location : Cytoplasm.
