本公司经销Brn-2，大脑蛋白2抗体，克隆类型为polyclonal，宿主来源是Rabbit，Brn-2大脑蛋白2抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-8508R
英文名称：Anti-Brn-2
中文名称：大脑蛋白2抗体
其他名称：Brain 2; Brain specific homeobox/POU domain protein 2; Brain-2; Brain-specific homeobox/POU domain protein 2; BRN 2; Brn-2; BRN2; N Oct 3; N OCT 3 Gene; Nervous system specific octamer binding transcription factor; Nervous system-specific octamer-binding transcription factor N-Oct-3; Oct-7; OCT7; Octamer Binding Transcription Factor 7; Octamer-binding protein 7; Octamer-binding transcription factor 7; OTF 7; OTF-7; OTF7; PO3F2_HUMAN; POU class 3 homeobox 2; POU domain class 3 transcription factor 2; POU domain, class 3, transcription factor 2; Pou3f2; POUF 3; POUF3; Protein Brn 2.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 49kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, pig, hrs, cow, dog, Rb
产品介绍：The Brn family of transcription factors are found in a highly restricted subset of neurons ａnd are critical to the early embryonic development of the central nervous system. Brn-1 ａnd Brn-2 are class III POU domain proteins. Expressed during the development of the forebrain ａnd coexpressed in most layer II-V cortical neurons, Brn-1 ａnd Brn-2 appear to critically control the initiation of radial migration of cortical neurons. Brn-2 is thought to be involved in smooth muscle cell development ａnd differentiation. Brn-3 is a class IV POU domain protein. Three Brn-3 proteins have been described ａnd are designated Brn-3a, Brn-3b ａnd Brn-3c. Brn-3a has two functional transactivating domains, one at the amino terminus ａnd one at the carboxy terminus. While Brn-3a ａnd Brn-3c stimulate transcription, Brn-3b generally functions as a transcriptional repressor. However, Brn-3b, but not Brn-3a, has been shown to regulate the expression of the acetylcholine receptor.Subunit : Interacts with PQBP1.Subcellular Location : Nucleus.Tissue Specificity : Expressed specifically in the neuroectodermal cell lineage.Similarity : Belongs to the POU transcription factor family. Class-3 subfamily.Contains 1 homeobox DNA-binding domain.Contains 1 POU-specific domain.