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Anti-Phospho-BMX/ETK (Tyr40)磷酸化非受体性蛋白酪氨酸激酶ETK抗体
点击次数：200发布时间：2012/12/26 7:07:47
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-3132R
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详细内容
货号：BY-3132R
英文名称：Anti-Phospho-BMX/ETK （Tyr40）
中文名称：磷酸化非受体性蛋白酪氨酸激酶ETK抗体
其他名称：BMX; NKT38; NTK 38; Protein tyrosine kinase BMX; PSCTK 2; PSCTK 3; PSCTK2; PSCTK3; Bone marrow tyrosine kinase gene in chromosome X protein; BMX non receptor tyrosine kinase; Cytoplasmic tyrosine protein kinase BMX; Epithelial ａnd endothelial tyrosine kinase.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 78kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cow, hrs, dog, pig, Rb
产品介绍：This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate （PIP3）, ａnd a SH2 domain that binds to tyrosine-phosphorylated proteins ａnd functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, ａnd regulates differentiation ａnd tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].Subcellular Location : Cytoplasm.Tissue Specificity : Highly expressed in cells with great migratory potential, including endothelial cells ａnd metastatic carcinoma cell lines.Similarity : Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily. Contains 1 Btk-type zinc finger. Contains 1 PH domain. Contains 1 protein kinase domain. Contains 1 SH2 domain.Etk属非受体性蛋白酪氨酸激酶BTK家族成员，主要表达于上皮和内皮细胞，在调控细胞的增殖及凋亡等信号转导过程中起着重要的作用。Etk与肿瘤发生发展、分化增值密切相关。
