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Anti-BCHE (CT)丁酰胆碱酯酶抗体(C端)
点击次数:244发布时间:2012/12/26 7:08:44
更新日期:2024/9/5 14:43:27
所 在 地:其它
产品型号:BY-0987R
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货号:BY-0987R
英文名称:Anti-BCHE (CT)
中文名称:丁酰胆碱酯酶抗体(C端)
其他名称:Cholinesterase; Acylcholine acylhydrolase; Choline esterase II; CHE1; Butyrylcholine esterase; Pseudocholinesterase.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 66kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, Rb, dog, hrs, pig, chk
产品介绍:Butyrylcholinesterase is synthetizised in the liver, and is predominantly found in serum, liver and pancreas. This enzyme is a tetrameric glycoprotein (molecular mass of 350 kDa), and consists of four subunits. Defects in Butyrylcholinesterase are the cause of a metabolic disorder characterized by prolonged apnoea after the use of certain anesthetic drugs, including the muscle relaxants succinylcholine or mivacurium and other ester local anesthetics.丁酰胆碱酯酶Bche又称假性胆碱酯酶。该酶主要分布于脑白质(中脑,桥脑,延脑,纹状体及丘脑等脑干区域),也分布于心血管系统、呼吸系统、消化系统等组织及腺体中,专一性水解丁酰胆碱酯而发挥其生理功能。目前有用于老年痴呆AD病方面的的研究。 (脊椎动物体内有两种胆碱酯酶:乙酰胆碱酯酶AchE,又叫真性胆碱酯酶。该酶不仅存在于胆碱能神经,也存在于非但碱能神经及其他组织,如胎盘、红细胞等,专一水解Ach;在一种就是丁酰胆碱酯酶Bche)产品图片Antigen: bs-0987P, 0.2ug/100ul Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Goat-Anti- Rabbit IgG(bs-0295G-HRP) at 1: 5000; TMB(C-0024) staining; Read the data in MicroplateReader by 450nm.