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货号：BY-7891R
英文名称：Anti-Cyclin T2
中文名称：周期素T2抗体
其他名称：CCNT2; CCNT2_HUMAN; Cyclin-T2; CycT2; FLJ90560; MGC134840.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 80kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, chk, cow, pig, hrs, Rb
产品介绍：Regulatory subunit of the cyclin-dependent kinase pair （CDK9/cyclin T） complex, also called positive transcription elongation factor B （P-TEFB）, which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD （carboxy-terminal domain） of the large subunit of RNA polymerase II （RNAP II）.Function : Regulatory subunit of the cyclin-dependent kinase pair （CDK9/cyclin T） complex, also called positive transcription elongation factor B （P-TEFB）, which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD （carboxy-terminal domain） of the large subunit of RNA polymerase II （RNAP II）.Subunit : Associates with CDK9 to form P-TEFb. Isoform 1 ａnd isoform 2 interact with HIV-2 ａnd SIV Tat. Does not bind efficiently to the transactivation domain of the HIV-1 Tat.Subcellular Location : Nucleus.Tissue Specificity : Ubiquitously expressed.Similarity : Belongs to the cyclin family. Cyclin C subfamily.
