产品展示
Anti-CADM2/IGSF4D/Cell adhesion molecule 2细胞粘附分子2
点击次数：233发布时间：2012/12/26 7:23:34
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-8246R
优质供应
详细内容
货号：BY-8246R
英文名称：Anti-CADM2/IGSF4D/Cell adhesion molecule 2
中文名称：细胞粘附分子2
其他名称：CADM2;CADM2_HUMAN;Cell adhesion molecule 2;IgSF4D;Immunoglobulin superfamily member 4D;NECL 2;Necl 3;NECL-3;NECL2;Necl3;Nectin like protein 3;Nectin-like protein 3;synCAM 2;synCAM2.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 48kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：Ig （immunoglobulin） superfamily members exhibit functional characteristics including immune responses, growth factor signaling ａnd cell adhesion. IGSF4D （Ig superfamily member 4D） is also known as CADM2 （cell adhesion molecule 2）, Necl-3 （nectin-like protein 3） or synCAM2 ａnd is a 435 amino acid protein that is a member of the nectin family. IGSF4D contains two C2-type domains ａnd one V-type domain, which are characteristic of the nectin family ａnd are thought to function in molecular recognition. IGSF4D is expressed in many tissues, including brain, where it is detected in the nervous system, specifically in myelinated axons ａnd ependymal cells. IGSF4D is localized to the plasma membrane as a single-pass membrane protein ａnd is expressed as three isoforms. IGSF4D functions in the regulation of cell–cell adhesion by homophilic ａnd heterophilic interactions leading to cell aggregation. These interactions are also important for neuron–neuron or neuron–glia associations, which are important for the development ａnd function of the central nervous system. IGSF4D is downregulated in lung cancer, suggesting a possible role in tumor suppression.
