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Anti-Calcineurin B/PP2B-B1钙调磷酸酶B亚基B1抗体
点击次数:184发布时间:2012/12/26 7:40:08
更新日期:2024/9/5 14:43:27
所 在 地:其它
产品型号:BY-11246R
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货号:BY-11246R
英文名称:Anti-Calcineurin B/PP2B-B1
中文名称:钙调磷酸酶B亚基B1抗体
其他名称:Calcineurin subunit B type 1;CALNB1;CANB1_HUMAN;Cna2;CNB;CNB1;OTTHUMP00000201960;OTTHUMP00000201961;Ppp3r1;PPP3R1 protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform;alpha isoform (calcineurin B, type I);calcineurin B, type I (19kDa);protein phosphatase3 (formerly2B), regulatory subunit B, alpha isoform antibodyProtein phosphatase 2B regulatory subunit 1;Protein phosphatase 2B regulatory subunit B alpha;protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I);Protein phosphatase 3 regulatory subunit B alpha;Protein phosphatase 3 regulatory subunit B alpha isoform 1.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 19kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat
产品介绍:In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunit have been identified, designated PP1, PP2A, PP2B and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4), is a putative member of a novel PP family. The PP2B family comprises subfamily members PP2B-A alpha, PP2B-A Beta and PP2B-A Gamma. Two additional regulatory subunits been identified, designated PP2B-B1 and PP2B-B2.Function : Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.Similarity : Belongs to the calcineurin regulatory subunit family.Contains 4 EF-hand domains.