本公司经销CCT2/TCP1 beta，分子伴侣复合体TCP-1β抗体，克隆类型为polyclonal，宿主来源是Rabbit，CCT2/TCP1 beta分子伴侣复合体TCP-1β抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-11267R
英文名称：Anti-CCT2/TCP1 beta
中文名称：分子伴侣复合体TCP-1β抗体
其他名称：CCT 2;CCT beta;CCT-beta;CCT-2;CCTB;Chaperonin containing t complex polypeptide 1 beta subunit;Chaperonin containing t complex polypeptide 1 subunit 2;Chaperonin containing TCP1 subunit 2;Chaperonin containing TCP1 subunit 2 （beta）;CTP:phosphocholine cytidylyltransferase 2;MGC142074;MGC142076;MGC94480;PRO1633;T complex protein 1 beta subunit;T complex protein 1 subunit beta;T-complex protein 1 subunit beta;TCP 1 beta;TCP-1-beta;TCPB_HUMAN;99D8.1.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 57 kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, Rb, cow, pig, zebrafish
产品介绍：CCT2 is one of eight largely unrelated subunit proteins found in a protein chaperone complex known as the chaperonin-containing TCP-1 （CCT） or TRiC complex. The CCT complex is an abundanct cytoslic component that is credited with helping newly synthesized polypeptides adopt the correct conformation （1）. Proteins that fold ａnd assemble with the help of CCT include the cytoskeletal proteins actin ａnd tubulin as well as up to 15% of newly synthesized eukaryotic proteins （2）. CCT2 is the β-subunit of the chaperone complex ａnd is one of several CCT proteins that exhibit increased expression in response to stress. This implies that the CCT complex helps cells recover from protein damage by assisting in protein folding ａnd assembly （3）. CCT subunit levels also change throughout the cell cycle, with lower proteins levels （and reduced chaperone activity） found during induced cell cycle arrest during at M phase （4）. Each CCT subunit is thought to perform a specific function during protein folding ａnd assembly （5）; CCT2 exhibits both actin ａnd tubulin binding activities （6,3） but the exact molecular function on this subunit remains uncertain.Function : Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin ａnd tubulin.Subcellular Location : Cytoplasm.Similarity : Belongs to the TCP-1 chaperonin family.