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Anti-C1QBP/GC1q R透明质酸结合蛋白1抗体
点击次数：210发布时间：2012/12/26 7:45:28
更新日期：2024/9/5 14:43:40
所 在 地：其它
产品型号：BY-11263R
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货号：BY-11263R
英文名称：Anti-C1QBP/GC1q R
中文名称：透明质酸结合蛋白1抗体
其他名称：C1q globular domain binding protein;C1QBP;C1QBP_HUMAN antibodyComplement component 1 q subcomponent binding protein;Complement component 1 Q subcomponent binding protein mitochondrial;Complement component 1 Q subcomponent-binding protein, mitochondrial;GC1Q R;GC1q R protein;GC1q-R protein;GC1QBP;GC1QR;Glycoprotein gC1qBP;HABP 1;HABP1;Hyaluronan binding protein 1;Hyaluronan-binding protein 1;Mitochondrial matrix protein p32;p32 antibodyp33 antibodyPre mrna splicing factor SF2 P32 subunit precursor;SF2p32;Splicing factor SF2 associated protein.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 33kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：The human complement subcomponent C1q associates with C1r ａnd C1s in order to yield the first component of the serum complement system （SCS）. The SCS contains over 30 glycoproteins that influence physiological mechanisms of the body in response to immune complex （the classical pathway）, carbohydrate （the lectin pathway） or bacterial （alternative pathway） initiation. C1q binding protein （C1QBP）, also designated gC1q-R, p32 （p33） or HABP1 （hyaluronan-binding protein 1）, is known to bind the globular heads of C1q molecules ａnd inhibit C1 activation. C1QBP has been described as a complement receptor for C1q on B cells, neutrophils ａnd mast cells. The C1QBP protein may form homodimers. C1QBP is expressed in vascular endothelial cells ａnd has been found to be a multifunctional protein interacting with elements of complement, coagulation ａnd kinin systems. In addition, C1QBP is a subunit of pre-mRNA splicing factor SF2/ASF.Function : Binds to the globular "heads" of C1Q thus inhibiting C1 activation.Subcellular Location : Mitochondrion matrix. Nucleus. Might also be nuclear in some cell types.Tissue Specificity : Similarity : Belongs to the MAM33 family.
