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Anti-CLSTN2老年痴呆相关类钙粘蛋白CS2抗体
点击次数：191发布时间：2012/12/26 7:47:11
更新日期：2024/9/5 14:43:40
所 在 地：其它
产品型号：BY-11339R
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货号：BY-11339R
英文名称：Anti-CLSTN2
中文名称：老年痴呆相关类钙粘蛋白CS2抗体
其他名称：Alc;Alcadein;Alcadein Gamma;Alcagamma;Alzheimer＇s disease related cadherin like protein;Calsyntenin 2;CLSTN 2;CS 2;CS2;FLJ39113;FLJ39499;MGC119560.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：
纯化方法：affinity purified by Protein A
交叉反应：hu, rat
产品介绍：Members of the calsyntenin protein family are localized to the post-synaptic membrane of exicitatory central nervous system （CNS） synapses. Calsyntenin-2, also known as Alcadein-gamma, is a 955 amino acid protein that localizes to the endoplasmic reticulum, golgi apparatus ａnd plasma membranes. Containing 2 cadherin-like repeats in its N-terminal extracellular region, calsyntenin-2 binds synaptic calcium with its cytoplasmic domain, suggesting a role in the modulation of calcium-mediated postsynaptic signals. Under normal physiological conditions, calsyntenin-2 is protoeolytically processed in an event in which the primary zeta-cleavage generates a short C-terminal transmembrane fragment ａnd a long extracellular N-terminal domain.Function : CLSTN2 （Alcadein gamma/Calsyntenin 2） is a member of the novel calsyntenin family of proteins that have been found to be localized in the postsynaptic membrane of excitatory central nervous system （CNS） synapses. It may play a role in postsynaptic Ca2+ signaling. Calsyntenin 2 structure is very similar to calsyntenin 1 in it＇s extracellular parts, but varies considerably in it＇s cytoplasmic segment.Subcellular Location : Membrane; single-pass type I membrane protein"
