产品展示
Anti-CCDC56卷曲螺旋结构域蛋白56抗体
点击次数:212发布时间:2012/12/26 8:04:57
更新日期:2024/9/5 14:43:40
所 在 地:其它
产品型号:BY-8116R
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货号:BY-8116R
英文名称:Anti-CCDC56
中文名称:卷曲螺旋结构域蛋白56抗体
其他名称:CCD56_HUMAN;CCDC56;Coiled-coil domain-containing protein 56;HSPC009.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:
纯化方法:affinity purified by Protein A
交叉反应:Human
产品介绍:The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC56 (coiled-coil domain containing 56) is a 106 amino acid single-pass membrane protein encoded by a gene that maps to human chromosome 17q21. Encoding over 1,200 genes, chromosome 17 comprises over 2.5% of the human genome. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome."