产品展示
Anti-CCDC116卷曲螺旋结构域蛋白116抗体
点击次数：221发布时间：2012/12/26 8:10:23
更新日期：2024/9/5 14:43:40
所 在 地：其它
产品型号：BY-8111R
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详细内容
货号：BY-8111R
英文名称：Anti-CCDC116
中文名称：卷曲螺旋结构域蛋白116抗体
其他名称：CC116_HUMAN;Ccdc116;Coiled-coil domain-containing protein 116.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：
纯化方法：affinity purified by Protein A
交叉反应：Human
产品介绍：CCDC116 is a 515 amino acid protein that exists as two alternatively spliced isoforms. Encoded by a gene that maps to human chromosome 22q11.21, CCDC116 is induced by curcumin （diferulolylmethane）, although its role is unclear. CCDC116 is significantly affected by dietary curcumin, which may have a protective role in inflammatory bowel disease （IBD） ａnd may reduce the relapse rate in human ulcerative colitis （UC）. As the second smallest human chromosome, chromosome 22 contains over 500 genes ａnd about 49 million bases. Phelan-McDermid syndrome, Neurofibromatosis type 2 ａnd autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 ａnd studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocation between chromosomes 9 ａnd 22 may lead to the formation of Philadelphia Chromosome ａnd subsequent production of a novel fusion protein known as BCR-Abl, a potent cell proliferation activator found in several types of leukemia."
