产品展示
Anti-CCDC138卷曲螺旋结构域蛋白138抗体
点击次数：234发布时间：2012/12/26 8:11:56
更新日期：2024/9/5 14:43:40
所 在 地：其它
产品型号：BY-8114R
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详细内容
货号：BY-8114R
英文名称：Anti-CCDC138
中文名称：卷曲螺旋结构域蛋白138抗体
其他名称：CCDC 138;CCDC138;Coiled coil domain containing 138;Coiled coil domain containing protein 138;coiled-coil domain containing 138;FLJ 32745;FLJ32745.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 76kDa
纯化方法：affinity purified by Protein A
交叉反应：Human
产品介绍：CCDC138, also known as FLJ32745, is a 685 amino acid protein expressed as two isoforms produced by alternative splicing. The gene that encodes CCDC138 maps to human chromosome 2q12.3. The second largest human chromosome, chromosome 2 consists of 237 million bases, encodes over 1,400 genes ａnd makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare ａnd morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 ａnd ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere ａnd vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.
