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Anti-CNTNAP3接触蛋白相关蛋白3抗体
点击次数:231发布时间:2012/12/26 8:21:43
更新日期:2024/9/5 14:43:40
所 在 地:其它
产品型号:BY-11075R
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货号:BY-11075R
英文名称:Anti-CNTNAP3
中文名称:接触蛋白相关蛋白3抗体
其他名称:CASPR3;Cell recognition molecule Caspr3;CNTNAP3A;Contactin associated protein like 3;contactin associated protein-like 3B;FLJ14195;KIAA1714.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 141kDa
纯化方法:affinity purified by Protein A
交叉反应:hu
产品介绍:CNTNAP3B is a 1,288 amino acid protein that is encoded by a gene which maps to human chromosome 9. Chromosome 9 contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in translocations that lead to the aberrant production of a BCR-ABL fusion protein often found in leukemias.Function : The protein encoded by this gene belongs to the NCP family of cell-recognition molecules. This family represents a distinct subgroup of the neurexins. NCP proteins mediate neuron-glial interactions in vertebrates and glial-glial contact in invertebrates. The protein encoded by this gene may play a role in cell recognition within the nervous system. Alternatively spliced transcript variants encoding different isoforms have been described but their biological nature has not been determined.Subcellular Location : Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 2: Secreted