本公司经销phospho-CPLA2 （Ser505），磷酸化胞浆型磷脂酶A2抗体，克隆类型为polyclonal，宿主来源是Rabbit，phospho-CPLA2 （Ser505）磷酸化胞浆型磷脂酶A2抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-8572R
英文名称：Anti-phospho-CPLA2 （Ser505）
中文名称：磷酸化胞浆型磷脂酶A2抗体
其他名称：phospho-CPLA2（Ser505）; p-CPLA2 （Ser505）; Calcium dependent phospholipid binding protein; CPLA 2; cPLA2 alpha; cPLA2; Cytosolic phospholipase A2; Cytosolic phospholipase A2 group IVA; Lysophospholipase; MGC126350; PA24A_HUMAN; Phosphatidylcholine 2 acylhydrolase; Phosphatidylcholine 2-acylhydrolase; Phospholipase A2 group 4 A; Phospholipase A2 group IVA （cytosolic calcium dependent）; Phospholipase A2 group IVA; PhospholipaseA2; PLA2G4.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 82kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, Rb, hrs
产品介绍：This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins ａnd leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, ａnd other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca（2+） levels ａnd phosphorylation, resulting in its translocation from the cytosol ａnd nucleus to perinuclear membrane vesicles. [provided by RefSeq, Jul 2008].Function : Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response.Subunit : Interacts with KAT5.Subcellular Location : Cytoplasm. Cytoplasmic vesicle. Note=Translocates to membrane vesicles in a calcium-dependent fashion.Tissue Specificity : Expressed in various tissues such as macrophages, platelets, neutrophils, fibroblasts ａnd lung endothelium.Post-translational modifications : Activated by phosphorylation at both Ser-505 ａnd Ser-727.Similarity : Contains 1 C2 domain.Contains 1 PLA2c domain.