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Anti-CDHF15/FAT3钙粘蛋白15抗体
点击次数：236发布时间：2012/12/26 8:23:59
更新日期：2024/9/5 14:43:40
所 在 地：其它
产品型号：BY-11081R
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货号：BY-11081R
英文名称：Anti-CDHF15/FAT3
中文名称：钙粘蛋白15抗体
其他名称：Cadherin family member 15;CDHF15;CDHR10;FAT tumor suppressor homolog 3;Fat3;FAT3_HUMAN;hFat3;Protocadherin Fat 3.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 512kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell to cell binding that is critical for the maintenance of structure ａnd morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including ∫-catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins ａnd desmocollins. FAT3 （FAT tumor suppressor homolog 3, also known as CDHF15 or CDHR10, is a 4,589 amino acid single-pass type I membrane protein expressed in ES cells, primitive neuroectoderm, fetal brain, infant brain, adult neural tissues ａnd prostate. Containing thirty-three cadherin domains, four EGF-like domains ａnd one laminin G-like domain, FAT3 may participate in the interactions between neurites derived from specific subsets of neurons during development.Function : May play a role in the interactions between neurites derived from specific subsets of neurons during development.Subcellular Location : Membrane; Single-pass type I membrane protein （Potential）.Tissue Specificity : Expressed in ES cells, primitive neuroectoderm, fetal brain, infant brain, adult neural tissues ａnd prostate.Similarity : Contains 33 cadherin domains.Contains 4 EGF-like domains.Contains 1 laminin G-like domain.
