产品展示
Anti-CRIPT突触后蛋白CRIPT抗体
点击次数：200发布时间：2012/12/26 8:25:57
更新日期：2024/9/5 14:43:40
所 在 地：其它
产品型号：BY-11021R
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详细内容
货号：BY-11021R
英文名称：Anti-CRIPT
中文名称：突触后蛋白CRIPT抗体
其他名称：CRIPT;CRIPT_HUMAN;Cysteine rich interactor of PDZ3;Cysteine rich PDZ binding protein;Cysteine-rich interactor of PDZ three;Cysteine-rich interactor of PDZ3;Cysteine-rich PDZ-binding protein;HSPC139;HSPC139 protein;Hypothetical protein CRIPT;Postsynaptic protein CRIPT.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 11kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：The PSD-95/SAP 90 family of proteins, which are known to bind to ａnd cluster various membrane proteins, are involved in the organization of synaptic structure. These proteins are physically ａnd functionally linked to cytoskeletal and/or signaling proteins. CRIPT （for cysteine-rich interactor of PDZ three）, a novel postsynaptic protein, binds specifically to the PDZ3 domain of PSD-95/SAP 90. CRIPT induces the recruitment of PSD-95/SAP 90 to microtubules, ａnd it has been shown to bind directly to microtubules, indicating that it may be responsible for cytoskeletal anchoring of PSD-95/SAP 90. CRIPT is widely expressed outside of the brain ａnd is highly conserved from animals to plants suggesting a wider role in regulating cytoskeleton-membrane associations.Function : Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses.Subcellular Location : Cytoplasm. Cell junction > synapse. Cell projection > dendritic spine. Colocalizes with DLG4 in asymmetric synapses.
