本公司经销CD1A，T淋巴细胞CD1抗体，克隆类型为polyclonal，宿主来源是Rabbit，CD1AT淋巴细胞CD1抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-4961R
英文名称：Anti-CD1A
中文名称：T淋巴细胞CD1抗体
其他名称：CD 1a;CD1;CD1a;CD1A;CD1A Antigen;CD1A antigen, a polypeptide;CD1a molecule;CD1A_HUMAN;cluster of differentiation 1 A;Cortical thymocyte antigen CD1A;differentiation antigen CD1 alpha 3;Epidermal dendritic cell marker CD1a;FCB 6;FCB6;HTA 1;HTA1;hTa1 thymocyte antigen;OTTHUMP00000018907;R 4;R4 antibodyT 6;T Cell Surface Antigen Leu 6;T Cell Surface Antigen T6;T cell surface antigen T6/Leu 6;T Cell Surface Glycoprotein CD1A;T-cell surface antigen T6/Leu-6;T-cell surface glycoprotein CD1a;T6 antibodyThymocyte Antigen CD1A.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 34kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D ａnd 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen ａnd has been shown to present lipid antigens for recognition by T lymphocytes. CD1 antigens are associated with ∫-2-Microglobulin ａnd expressed on cortical thymocytes, Langerhans cells, a B cell subset ａnd some dendritic cells. Specifically, CD1A is a marker for Langerhans cell histiocytosis （LCH） ａnd is found on interdigitating cells. Adaptor-protein complexes ａnd CD1-associated chaperones control CD1 trafficking, ａnd the development ａnd activation of CD1-restricted T cells. Constitutive endocytosis of CD1B molecules ａnd the differential sorting of MHC class II from lysosomes separate peptide- ａnd lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells. The human CD1 genes are all closely linked in a cluster mapping at chromosome 1q23.1.Function : Antigen-presenting protein that binds self ａnd non-self lipid ａnd glycolipid antigens ａnd presents them to T-cell receptors on natural killer T-cells.Subcellular Location : Cell membrane. Endosome membrane. Subject to intracellular trafficking between the cell membrane ａnd endosomes. Localizes to cell surface lipid rafts.Tissue Specificity : Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, ａnd in various other tissues.Similarity : Contains 1 Ig-like （immunoglobulin-like） domain.